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Factory Direct Supply Sr9011 CAS 1379686-29-9 Powder

The C-terminal of SR9011 family proteins lacks the domain that can bind to ligands, but the expression of Rev-erb proteins can be inhibited by recruiting nuclear receptor inhibitor factors and histone deacetylase 3. Histone deacetylase 3, a Rev-erb agonist, is a small molecule chemical probe. Fon-taine et al. first reported the correlation between SR9011 and inflammation in Chemicalbook. SR9011 can inhibit the expression of Tr4, so as to control inflammatory signals. Foreign scholars have found that in human macrophages, increasing the mRNA expression of SR9011 by pharmacological methods directly leads to a decrease in the mRNA expression of the pro-inflammatory factor interleukin 6.

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