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Tapentadol is a dual-action medication that combines opioid receptor agonism and norepinephrine reuptake inhibition. It binds to opioid receptors in the brain, similar to other opioids, to provide analgesic effects. Additionally, it inhibits the reuptake of norepinephrine, a neurotransmitter involved in the transmission of pain signals, which can further enhance its pain-relieving properties.

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